Semaglutide for weight loss: why regain weight after stopping. Share on PinterestTaking semaglutide medications like Wegovy and Ozempic may help individuals shed weight, however they typically regain misplaced kilos as soon as they cease semaglutide.
- Analysis has discovered that when individuals cease utilizing semaglutide for weight loss, weight rebound happens.
- Consultants say it’s because the drug is just not a remedy and it doesn’t stop the metabolic adaptation that happens throughout weight reduction.
- Lengthy-term adjustments in weight loss plan and exercise are an essential a part of sustaining weight reduction.
- Additionally it is essential to seek the advice of with a doctor earlier than utilizing weight reduction drugs.
Latest analysis printed within the journal Diabetes, Weight problems and Metabolism signifies that when sufferers cease utilizing semaglutide medicine like Wegovy and Ozempic any weight they’ve misplaced is more likely to return.
In keeping with Dr. Ibiye Owei, Assistant Professor at Texas Tech College. Well being Sciences Heart El Paso, semaglutide for weight loss is a glucagon-like-peptide-1 agonist (GLP-1 agonist). Which has been accepted by the Meals and Drug Administration (FDA) to deal with diabetes and weight problems or chubby.
“It really works by making individuals really feel full sooner and suppressing the urge for food so individuals don’t really feel as hungry,” she defined. “One of many methods it does that is by slowing emptying of the abdomen so there’s a feeling of satiety.”
Owei added that anybody with weight problems outlined as a. Physique Mass Index (BMI) of 30 and above or a BMI of 27 and above who’s experiencing weight-related problems corresponding to hypertension or sort 2 diabetes could be a great candidate to make use of this remedy.
In keeping with Dr. Kathleen Dungan, an endocrinologist within the Division of Endocrinology,. Diabetes & Metabolism at The Ohio State College Wexner Medical Heart,
there are a number of potential advantages to utilizing semaglutide for weight loss.
“It is likely one of the best therapies obtainable for both situation, exterior of bariatric surgical procedure,” stated Dungan. “Furthermore, there may be proof that using semaglutide could scale back the chance for growing diabetes and could also be notably helpful in people who’ve prediabetes.”
Whereas medicine like Wegovy and Ozempic may seem to be a miracle to these with diabetes and weight problems. The reality is the consequences solely final if you are taking the remedy.
A research printed in April 2022 which sought to look at adjustments in physique weight and cardiometabolic threat components upon the termination of the drug,
discovered that after a yr semaglutide individuals had regained two-thirds of the burden that they had misplaced.
The constructive adjustments that they had seen in cardiometabolic threat components like blood stress, blood lipids, HbA1c, and C-reactive protein had equally reversed.
In keeping with the research authors, these findings reinforce the necessity to proceed remedy as a way to keep the advantages of the remedy.
In keeping with Dungan, weight rebound happens fairly just because the drug doesn’t remedy the underlying points that led to weight acquire within the first place.
Content material creator,. Remi Bader not too long ago made a visitor look on the podcast ‘Not Skinny However Not Fats’. Tto share that she had not solely “gained double the burden again” as soon as she stopped taking Ozempic. However her “binging received a lot worse.”
“I noticed a health care provider, and so they have been like. It’s 100% as a result of I went on Ozempic,”. Bader shared through the podcast episode.
Owei defined that metabolic adaptation happens whereas sufferers are reducing weight and this will contribute to weight acquire when the remedy is ended.
Nonetheless, she stated that this impact isn’t distinctive to semaglutide for weight loss.
“This occurs no matter what weight reduction technique is employed,”. She stated, declaring a research exhibiting that contestants of the TV present “The Greatest Loser”. Had skilled a lower in resting metabolic charge that also continued 6 years after the competitors had ended.
Dungan stated the optimum length of use for semaglutide is just not recognized. Nonetheless, since you could regain weight when you cease the drug, you will need to make adjustments in your way of life as effectively.
“semaglutide for weight loss is just not an alternative choice to weight loss plan and train,”. She stated, “however is usually a very efficient remedy.”
Owei added that research have proven that weight problems is a continual illness. So long-term remedy could be vital as a way to stop weight regain.
“Nonetheless, I’d at all times weigh the chance of utilizing a drugs in opposition to the advantages in making any resolution for long-term use,” she stated.
There are some probably severe negative effects that may happen with this remedy. She famous, together with pancreatitis, kidney failure, and medullary thyroid most cancers. There may be additionally the potential of threat to a growing fetus.
Train will also be useful in weight upkeep after reducing weight on semaglutide for weight loss. She stated, explaining that the contestants talked about beforehand have been aided of their upkeep efforts by growing bodily exercise.
“As we all know,” she stated, “all research have strengths and weaknesses and most are usually not reproducible. However these way of life adjustments are essential to each weight reduction and upkeep along with remedy use.”
Owei added that you will need to verify in together with your healthcare supplier. Or a doctor licensed in weight problems administration previous to utilizing weight reduction remedy.
“Like some other continual illness, it requires long-term administration,” she concluded.
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